The eye lens consists of a layer of epithelial cells that overlay a series of differentiating fiber
cells that upon maturation lose their mitochondria, nuclei and other organelles. Lens
transparency relies on the metabolic function of mitochondria contained in the lens epithelial
cells and in the immature fiber cells and the programmed degradation of mitochondria and
other organelles occurring upon lens fiber cell maturation. Loss of lens mitochondrial
function in the epithelium or failure to degrade mitochondria and other organelles in lens …