Autophagy-related lipase FgATG15 of Fusarium graminearum is important for lipid turnover and plant infection
LN Nguyen, J Bormann, GTT Le, C Stärkel… - Fungal Genetics and …, 2011 - Elsevier
Autophagy is a non-selective degradation pathway in eukaryotic cells that is conserved from
yeasts to humans. Autophagy is involved in the virulence of several pathogenic fungi such
as Magnaporthe grisea or Colletotrichum orbiculare. In the current study, we identified and
disrupted an autophagy-like lipase FgATG15 in Fusarium graminearum. We showed that
FgATG15 exhibits lipase activity when heterologously expressed in P. pastoris. We used a
gene deletion approach to characterize the function of the enzyme. We demonstrate that …
yeasts to humans. Autophagy is involved in the virulence of several pathogenic fungi such
as Magnaporthe grisea or Colletotrichum orbiculare. In the current study, we identified and
disrupted an autophagy-like lipase FgATG15 in Fusarium graminearum. We showed that
FgATG15 exhibits lipase activity when heterologously expressed in P. pastoris. We used a
gene deletion approach to characterize the function of the enzyme. We demonstrate that …
Autophagy-related lipase FgATG15 of Fusarium graminearum is important for lipid turnover and plant infection.
LNN Long Nam Nguyen, J Bormann… - 2011 - cabidigitallibrary.org
Autophagy is a non-selective degradation pathway in eukaryotic cells that is conserved from
yeasts to humans. Autophagy is involved in the virulence of several pathogenic fungi such
as Magnaporthe grisea or Colletotrichum orbiculare. In the current study, we identified and
disrupted an autophagy-like lipase FgATG15 in Fusarium graminearum. We showed that
FgATG15 exhibits lipase activity when heterologously expressed in P. pastoris. We used a
gene deletion approach to characterize the function of the enzyme. We demonstrate that …
yeasts to humans. Autophagy is involved in the virulence of several pathogenic fungi such
as Magnaporthe grisea or Colletotrichum orbiculare. In the current study, we identified and
disrupted an autophagy-like lipase FgATG15 in Fusarium graminearum. We showed that
FgATG15 exhibits lipase activity when heterologously expressed in P. pastoris. We used a
gene deletion approach to characterize the function of the enzyme. We demonstrate that …
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