[PDF][PDF] Broad One Health Endectocide-based Malaria Intervention in Africa. A Phase III cluster-randomized, open-label, clinical trial to study the safety and efficacy of …

C Chaccour, A Casellas, F Hammann, P Ruiz-Castillo… - 2022 - scholar.archive.org
Background: Residual malaria transmission is the result of adaptive mosquito behavior that
allows malaria vectors to thrive and sustain transmission in the presence of good access to
bed nets or insecticide residual spraying. These behaviors include crepuscular and outdoor
feeding as well as intermittent feeding upon livestock. Ivermectin is a broadly used
antiparasitic drug that kills mosquitoes feeding on a treated subject for a dose-dependent
period. Mass drug administration with ivermectin has been proposed as a complementary …

BOHEMIA: Broad One Health Endectocide-based Malaria Intervention in Africa—a phase III cluster-randomized, open-label, clinical trial to study the safety and …

C Chaccour, A Casellas, F Hammann, P Ruiz-Castillo… - Trials, 2023 - Springer
Background Residual malaria transmission is the result of adaptive mosquito behavior that
allows malaria vectors to thrive and sustain transmission in the presence of good access to
bed nets or insecticide residual spraying. These behaviors include crepuscular and outdoor
feeding as well as intermittent feeding upon livestock. Ivermectin is a broadly used
antiparasitic drug that kills mosquitoes feeding on a treated subject for a dose-dependent
period. Mass drug administration with ivermectin has been proposed as a complementary …
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