Bcl-2-like protein 13 is a mammalian Atg32 homologue that mediates mitophagy and mitochondrial fragmentation

T Murakawa, O Yamaguchi, A Hashimoto… - Nature …, 2015 - nature.com
homologue has been identified in mammalian cells. Here, we show that Bcl-2-like protein
13 (Bcl2-L-13) induces mitochondrial fragmentation and mitophagy in mammalian cells. First, …

The mitophagy receptor Bcl-2like protein 13 stimulates adipogenesis by regulating mitochondrial oxidative phosphorylation and apoptosis in mice

M Fujiwara, L Tian, PT Le, VE DeMambro… - Journal of Biological …, 2019 - ASBMB
… identified Bcl-2like protein 13 (Bcl2l13), a mitochondrial mitophagy receptor, as … Bcl-2-like
protein 13 is a mammalian Atg32 homologue that mediates mitophagy and mitochondrial

A mammalian mitophagy receptor, Bcl2-L-13, recruits the ULK1 complex to induce mitophagy

T Murakawa, K Okamoto, S Omiya, M Taneike… - Cell reports, 2019 - cell.com
… we identified Bcl2-like protein 13 (Bcl2-L-13) as a mammalian functional homolog of …
Bcl-2-like protein 13 is a mammalian Atg32 homologue that mediates mitophagy and mitochondrial

Biological properties of the BCL-2 family protein BCL-RAMBO, which regulates apoptosis, mitochondrial fragmentation, and mitophagy

T Kataoka - Frontiers in Cell and Developmental Biology, 2022 - frontiersin.org
mitophagy is mediated by at least five mitophagy receptors … -2 family protein BCL-RAMBO,
also known as BCL2-like 13 (… a mammalian Atg32 homologue that regulates mitophagy and …

Bcl-2 family members and the mitochondrial import machineries: The roads to death

L Lalier, F Vallette, S Manon - Biomolecules, 2022 - mdpi.com
… β-Barrel proteins also exist in mammalian mitochondria such … [15] and mediates granzyme
B entry into mitochondria, which … mitophagy regulator ATG32, which is not a Bcl-2 homolog

[HTML][HTML] AMPK regulates Bcl2-L-13-mediated mitophagy induction for cardioprotection

T Murakawa, J Ito, MC Rusu, M Taneike, S Omiya… - Cell Reports, 2024 - cell.com
… , and phosphatase and tensin homolog-induced putative kinase protein 1 (… 13 as a functional
mammalian homolog of Atg32. Bcl2-L-13 induces both mitochondrial fission and mitophagy

BCL2L13: physiological and pathological meanings

F Meng, N Sun, D Liu, J Jia, J Xiao, H Dai - Cellular and Molecular Life …, 2021 - Springer
… eg, BAX [13] and BAK [14]; BH3-only pro-apoptotic proteins that … to LC3B as a mammalian
homologue of ATG32, in support … for BCL2L13 mediated mitophagy, whether the mitochondrial

1182 The novel mitophagic receptor protein bcl2-like protein 13: new insights for the molecular mechanisms of the pathogenesis of heart disease

T Murakawa, K Otsu - European Heart Journal, 2019 - academic.oup.com
… We hypothesized that an unknown mammalian mitophagy receptor will share the
molecular … protein database for Atg32 homologues, we identified Bcl-2-like protein 13 (Bcl2-L-13). …

BNIP3 (BCL2 interacting protein 3) regulates pluripotency by modulating mitochondrial homeostasis via mitophagy

K Liu, Q Zhao, H Sun, L Liu, C Wang, Z Li, Y Xu… - Cell death & …, 2022 - nature.com
… role of BNIP3-mediated mitophagy in the induction and … In yeast, ATG32 has been
demonstrated as a mitochondrial … autophagic degradation of mitochondria in mammalian cells. …

BCL2L13 promotes mitophagy through DNM1L-mediated mitochondrial fission in glioblastoma

J Wang, A Chen, Z Xue, J Liu, Y He, G Liu, Z Zhao… - Cell Death & …, 2023 - nature.com
… BCL2 like 13 (BCL2L13), a BLC2-like protein encoded by the … acts as a critical activator of
mitophagy in GBM cells. These … a mammalian homolog of the yeast mitophagy receptor Atg32 […