Behavioural and psychological symptoms of dementia in Down syndrome: Early indicators of clinical Alzheimer's disease?
Abstract Behavioural and Psychological Symptoms of Dementia (BPSD) are a core symptom
of dementia and are associated with suffering, earlier institutionalization and accelerated
cognitive decline for patients and increased caregiver burden. Despite the extremely high
risk for Down syndrome (DS) individuals to develop dementia due to Alzheimer's disease
(AD), BPSD have not been comprehensively assessed in the DS population. Due to the
great variety of DS cohorts, diagnostic methodologies, sub-optimal scales, covariates and …
of dementia and are associated with suffering, earlier institutionalization and accelerated
cognitive decline for patients and increased caregiver burden. Despite the extremely high
risk for Down syndrome (DS) individuals to develop dementia due to Alzheimer's disease
(AD), BPSD have not been comprehensively assessed in the DS population. Due to the
great variety of DS cohorts, diagnostic methodologies, sub-optimal scales, covariates and …
[PDF][PDF] Behavioural and psychological symptoms of dementia in Down syndrome: Early indicators of clinical
AD Dekkera, A Strydomc, AMW Coppusd, D Nizetice… - Brain & Development - core.ac.uk
Abstract Behavioural and Psychological Symptoms of Dementia (BPSD) are a core symptom
of dementia and are associated with suffering, earlier institutionalization and accelerated
cognitive decline for patients and increased caregiver burden. Despite the extremely high
risk for Down syndrome (DS) individuals to develop dementia, BPSD have not been
comprehensively assessed in the DS population. Due to the great variety of DS cohorts,
diagnostic methodologies, sub-optimal scales, covariates and outcome measures, it is …
of dementia and are associated with suffering, earlier institutionalization and accelerated
cognitive decline for patients and increased caregiver burden. Despite the extremely high
risk for Down syndrome (DS) individuals to develop dementia, BPSD have not been
comprehensively assessed in the DS population. Due to the great variety of DS cohorts,
diagnostic methodologies, sub-optimal scales, covariates and outcome measures, it is …
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