Prevention of cardiovascular events with calcium channel blocker-based combination therapies in patients with hypertension: a randomized controlled trial

…, Combination Therapy of Hypertension to … - … of hypertension, 2011 - journals.lww.com
… from the patients treated with benazepril-amlodipine or benazepril-hydrochlorothiazide as
recently … Because combination therapies are often needed for high-risk patients with cardiac …

Combined olmesartan, amlodipine, and hydrochlorothiazide therapy in randomized patients with hypertension: a subgroup analysis of the TRINITY study by age

AJ Lewin, JL Izzo, M Melino, J Lee, V Fernandez… - Drugs & aging, 2013 - Springer
HCTZ and/or AML is an effective and safe treatment for hypertension in a broad range of
patients… In one study, 52–67 % of study participants ≥65 years of age receiving OM/HCTZ

Blood pressure effects of high-dose amlodipine-benazepril combination in Black and White hypertensive patients not controlled on monotherapy

SG Chrysant - Drugs in R&D, 2012 - Springer
… in significant reductions in cardiovascular morbidity and mortality in high-risk hypertensive
patients compared with an atenolol–diuretic combination, for similar … with hydrochlorothiazide. …

Safety implications of combining ACE inhibitors with thiazides for the treatment of hypertensive patients

C Borghi, M Soldati, A Bragagni… - Expert Opinion on Drug …, 2020 - Taylor & Francis
… A population of over 11.000 patients with hypertension considered at high risk for … treatment
with either benazepril plus amlodipine or benazepril plus hydrochlorothiazide. The primary …

Comparison of two single-pill dual combination antihypertensive therapies in Chinese patients: a randomized, controlled trial

, … Therapy in Chinese Hypertensive Patients (ACvAD) … - BMC medicine, 2024 - Springer
amlodipine/benazepril and benazepril/hydrochlorothiazide dual therapies in Chinese patients.
… of our study is that in the Chinese patients with stage 1 to 2 hypertension the amlodipine/…

Efficacy and effects on lipid metabolism of combination treatment with losartan+ hydrochlorothiazide versus losartan+ amlodipine: a 48-week prospective, multicenter …

M Nishiwaki, H Hosoai, K Ikewaki, M Ayaori… - Clinical …, 2013 - Elsevier
patients aged 20 to 75 years with essential hypertension … with benazepril + HCTZ than with
benazepril + amlodipine … with an ACE inhibitor + HCTZ in the patients at high risk for CVD. In …

The Avoiding Cardiovascular events through COMbination therapy in Patients Living with Systolic Hypertension (ACCOMPLISH) trial: a comparison of first-line …

AB Weder - Expert Opinion on Pharmacotherapy, 2005 - Taylor & Francis
… 12,600 high-risk hypertensives to regimens of benazepril/amlodipine or benazepril/hydrochlorothiazide
Patients will be enrolled in the US (9000 patients at 500 sites), Sweden (2400 …

The Role of Combination Therapy for Hypertension After ACCOMPLISH

DT Lackland - Current Cardiovascular Risk Reports, 2010 - Springer
patients with hypertension and high risk for … (benazepril) in combination with CCB (amlodipine)
or to treatment with the combination of an ACE and diuretic (hydrochlorothiazide [HCTZ]). …

Efficacy and safety of triple antihypertensive therapy with the olmesartan/amlodipine/hydrochlorothiazide combination

M Volpe, LC Rump, B Ammentorp, P Laeis - Clinical drug investigation, 2012 - Springer
patients with moderate-to-severe hypertension assessed the efficacy and safety of adding
hydrochlorothiazide (HCTZ… of olmesartan medoxomil (OLM)/amlodipine (AML) doses. Study …

Olmesartan/amlodipine/hydrochlorothiazide in participants with hypertension and diabetes, chronic kidney disease, or chronic cardiovascular disease: a subanalysis …

DJ Kereiakes, SG Chrysant, JL Izzo, T Littlejohn… - Cardiovascular …, 2012 - Springer
… Despite the evidence supporting the benefit of targeted BP control in high-risk patient
groups, some investigators have raised questions regarding incremental benefit with more …