pathogens and alloantigens, and evidence suggests an important role for them in antitumor
immunity as well. Although major histocompatibility complex class II–restricted human CD4
T cells with specific antitumor reactivities have been described, no standard method exists
for cloning the recognized tumor-associated antigen (Ag). In this study, biochemical protein
purification methods were used in conjunction with novel mass spectrometry sequencing …