[HTML][HTML] Biological Activity of Cyclic Peptide Extracted from Sphaeranthus amaranthoides Using De Novo Sequencing Strategy by Mass Spectrometry for Cancer
S Yanamadala, S Shanthirappan, S Kannan… - Biology, 2023 - mdpi.com
Simple Summary Cancer therapy today has benefited from multifaceted approaches in early
detection and diagnosis, but weak prognosis still hinders progress, as it is a barricade for
guaranteed successful treatment. The present study checks the anticancer properties of
AMPs, or antimicrobial peptides, isolated from Sphaeranthus amaranthoides, a traditional
medicinal plant in a fibroblast cell line. A technique named 'de novo'sequencing was used
for identifying the biological potential of the isolated molecule. That molecule was …
detection and diagnosis, but weak prognosis still hinders progress, as it is a barricade for
guaranteed successful treatment. The present study checks the anticancer properties of
AMPs, or antimicrobial peptides, isolated from Sphaeranthus amaranthoides, a traditional
medicinal plant in a fibroblast cell line. A technique named 'de novo'sequencing was used
for identifying the biological potential of the isolated molecule. That molecule was …
[PDF][PDF] Biological Activity of Cyclic Peptide Extracted from Sphaeranthus amaranthoides Using De Novo Sequencing Strategy by Mass Spectrometry for Cancer …
S Yanamadala, S Shanthirappan, S Kannan… - 2023 - academia.edu
Though there are several advancements and developments in cancer therapy, the treatment
remains challenging. In recent years, the antimicrobial peptides (AMPs) from traditional
herbs are focused for identifying and developing potential anticancer molecules. In this
study, AMPs are identified from Sphaeranthus amaranthoides, a natural medicinal herb
widely used as a crucial immune stimulant in Indian medicine. A total of 86 peptide traces
were identified using liquid-chromatography–electrospray-ionisation mass spectrometry (LC …
remains challenging. In recent years, the antimicrobial peptides (AMPs) from traditional
herbs are focused for identifying and developing potential anticancer molecules. In this
study, AMPs are identified from Sphaeranthus amaranthoides, a natural medicinal herb
widely used as a crucial immune stimulant in Indian medicine. A total of 86 peptide traces
were identified using liquid-chromatography–electrospray-ionisation mass spectrometry (LC …