… Transdermal drug delivery systems that utilize transcutaneous patches of arrayed … or
skin-specific tissues to create bioresponsive patches that release drug directly in response to an …

… with transcutaneous patches of arrayed microneedles (MNs), researchers has focused on the
development of bioresponsive patches … several bioresponsive transdermal MN-patches for …

… on diabetic rats by the transdermal delivery is illustrated. … immunotherapy through a
transdermal MN vaccine patch. The … Table 2 summarizes representative bioresponsive MNs and …

Bioresponsive drug delivery systems - ScienceDirect …

… Herein, we will summarize and classify recent advances in the development of bioresponsive
transcutaneous patches, including pH-responsive, glucose-responsive, and enzyme-…

… transcutaneous patch could sense the thrombin levels in capillary blood circulation, and there
was little drug leaked from the patch … that this bioresponsive patch could effectively prevent …

… physical removal of the patch. The evolution of transdermal patches towards smarter, stimuli
… , electrical activation, light initiation and bioresponsive systems coming to the fore. These …

… Microneedle (MN) arrays are needles of 25 μm–2000 μm supported on a base or patch [52],
it was first conceptualized as a non-invasive parenteral (transdermal) drug delivery system …

… development of wearable patch for transdermal drug delivery. These patches are grouped
… Some of these bioresponsive MNs for insulin delivery have been seen in clinical trials 9 , 62 …

… Here, we show that a single removable transdermal patch, bearing microneedles loaded
with insulin and a non-degradable glucose-responsive polymeric matrix, and fabricated via in …