Blind validation of MSIntuit, an AI-based pre-screening tool for MSI detection from histology slides of colorectal cancer

C Saillard, R Dubois, O Tchita, N Loiseau, T Garcia… - medRxiv, 2022 - medrxiv.org
… In this study, we performed a blind clinical validation of MSIntuit on a large external cohort of
pre-screening tool, MSIntuit can rule out almost half of the non-MSI population to ease MSI

Validation of MSIntuit as an AI-based pre-screening tool for MSI detection from colorectal cancer histology slides

C Saillard, R Dubois, O Tchita, N Loiseau… - Nature …, 2023 - nature.com
… In this work, we perform a blind clinical validation of MSIntuit on a large external … MSIntuit
as a pre-screening tool can rule out almost half of the non-MSI population, thus easing MSI

920P Blind validation of MSIntuit, an AI-based pre-screening tool for MSI detection from colorectal cancer H&E slides

M Svrcek, C Saillard, R Dubois, N Loiseau… - Annals of …, 2022 - annalsofoncology.org
… dMMR/MSI cases) diagnosed at Medipath pathology laboratories … 30 dMMR/MSI WSI were
used to calibrate the tool on each … done on the remaining 570 patients blinded to their status. …

[HTML][HTML] Artificial intelligence in predicting microsatellite instability and KRAS, BRAF mutations from whole-slide images in colorectal cancer: a systematic review

T Guitton, P Allaume, N Rabilloud, N Rioux-Leclercq… - Diagnostics, 2023 - mdpi.com
… is already an AI-based pre-screening tool for MSI detection in … on an external validation on
the PIAP (pathology AI platform) … The MSIntuit reaches a sensitivity of 95% (CI: 95% [93–100%…

921P Application of machine learning algorithm for cytological diagnosis of thyroid cancer

E Lee, YK Lee, HS Min, SY Park, HY Lee… - Annals of …, 2022 - annalsofoncology.org
… a one-shot blind validation of MSIntuit on a large external … dMMR/MSI cases) diagnosed at
Medipath pathology laboratories in … blind validation of an AI-based tool for MSI detection from …

[HTML][HTML] Artificial intelligence in colorectal cancer: from patient screening over tailoring treatment decisions to identification of novel biomarkers

NG Reitsam, JS Enke, K Vu Trung, B Märkl, JN Kather - Digestion, 2024 - karger.com
AI-based techniques in CRC pathology. Yet, many of those … example, if only MSI/dMMR
testing via immunohistochemistry, … MSIntuit [94] for ruling out pMMR/MSS cases prior molecular …

AI in Colorectal Cancer: From Patient Screening over Tailoring Treatment Decisions to Identification of Novel Biomarkers

NG Reitsam, JS Enke, K Vu Trung, B Märkl, JN Kather - Digestion, 2024 - karger.com
… or molecular testing of prognostic and predictive biomarkers, such as MSI (… Validation of
MSIntuit as an AIbased pre-screening tool for MSI detection from colorectal cancer histology

Transformer-based biomarker prediction from colorectal cancer histology: A large-scale multicentric study

SJ Wagner, D Reisenbüchler, NP West, JM Niehues… - Cancer Cell, 2023 - cell.com
validated on small patient cohorts. Here, we develop a new transformer-based pipeline for
end-to-end biomarker prediction from pathology … of microsatellite instability (MSI) on surgical …

Overcoming the challenges to implementation of artificial intelligence in pathology

JS Reis-Filho, JN Kather - JNCI: Journal of the National Cancer …, 2023 - academic.oup.com
… approved methods for cancer detection in pathology slides are … analytical validity, clinical
validity, and clinical utility of AI-basedAI-based biomarkers would there be a clear incentive for …

[HTML][HTML] PAIP 2020: Microsatellite instability prediction in colorectal cancer

K Kim, K Lee, S Cho, DU Kang, S Park, Y Kang… - Medical Image …, 2023 - Elsevier
… This paper supports the effectiveness of digital pathology for … can thus be a useful pre-screening
tool for selecting colorectal … Deep learning solution, MSIntuit, which enables identifying …