[HTML][HTML] Bone marrow is the preferred site of memory CD4+ T cell proliferation during recovery from sepsis

T Skirecki, P Swacha, G Hoser, J Golab, D Nowis… - JCI insight, 2020 - ncbi.nlm.nih.gov
Sepsis survivors suffer from increased vulnerability to infections, and lymphopenia
presumably contributes to this problem. The mechanisms of the recovery of memory CD4+ T
cells after sepsis remain elusive. We used the cecal ligation and puncture mouse model of
sepsis to study the restoration of the memory CD4+ T cells during recovery from sepsis.
Then, adoptive transfer of antigen-specific naive CD4+ T cells followed by immunization and
BrdU labeling were performed to trace the proliferation and migration of memory CD4+ T …

[引用][C] Bone marrow is the preferred site of memory CD4+ T cell proliferation during recovery from sepsis. JCI Insight. 2020; 5: 1-17. DOI: 10.1172/JCI

T Skirecki, P Swacha, G Hoser, J Golab, D Nowis… - INSIGHT
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