Bovine colostrum inhibits nuclear factor κB–mediated proinflammatory cytokine expression in intestinal epithelial cells

MJ An, JH Cheon, SW Kim, JJ Park, CM Moon, SY Han… - Nutrition research, 2009 - Elsevier
Colostrum, a nutrient-rich fluid produced by female mammals immediately after giving birth,
is loaded with several immune, growth, and tissue repair factors. However, it remains
unknown whether bovine colostrum has anti-inflammatory effects on intestinal epithelial
cells (IEC). In this study, we aimed to investigate the anti-inflammatory effects of colostrum
on IEC and to elucidate its molecular mechanisms. Human colon cancer HT-29 cells were
stimulated with interleukin (IL)–1β with or without bovine colostrum. The effects of colostrum …
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