Brain connectivity is not only lower but different in schizophrenia: a combined anatomical and functional approach
P Skudlarski, K Jagannathan, K Anderson… - Biological …, 2010 - Elsevier
BACKGROUND: Schizophrenia is hypothesized to involve disordered connectivity between
brain regions. Currently, there are no direct measures of brain connectivity; functional and
structural connectivity used separately provide only limited insight. Simultaneous measure of
anatomical and functional connectivity and its interactions allow for better understanding of
schizophrenia-related alternations in brain connectivity. METHODS: Twenty-seven
schizophrenia patients and 27 healthy control subjects underwent magnetic resonance …
brain regions. Currently, there are no direct measures of brain connectivity; functional and
structural connectivity used separately provide only limited insight. Simultaneous measure of
anatomical and functional connectivity and its interactions allow for better understanding of
schizophrenia-related alternations in brain connectivity. METHODS: Twenty-seven
schizophrenia patients and 27 healthy control subjects underwent magnetic resonance …