BrumiR: A toolkit for de novo discovery of microRNAs from sRNA-seq data
MicroRNAs (miRNAs) are small noncoding RNAs that are key players in the regulation of
gene expression. In the past decade, with the increasing accessibility of high-throughput
sequencing technologies, different methods have been developed to identify miRNAs, most
of which rely on preexisting reference genomes. However, when a reference genome is
absent or is not of high quality, such identification becomes more difficult. In this context, we
developed BrumiR, an algorithm that is able to discover miRNAs directly and exclusively …
gene expression. In the past decade, with the increasing accessibility of high-throughput
sequencing technologies, different methods have been developed to identify miRNAs, most
of which rely on preexisting reference genomes. However, when a reference genome is
absent or is not of high quality, such identification becomes more difficult. In this context, we
developed BrumiR, an algorithm that is able to discover miRNAs directly and exclusively …
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