Buprenorphine–naloxone “microdosing”: an alternative induction approach for the treatment of opioid use disorder in the wake of North America's increasingly potent …
PA Randhawa, R Brar, S Nolan - Cmaj, 2020 - Can Med Assoc
PA Randhawa, R Brar, S Nolan
Cmaj, 2020•Can Med Assoc1. Bruneau J, Ahamad K, Goyer M-È, et al. Management of opioid use disorders: a national
clinical practice guideline. CMAJ 2018; 190: E247-57. 2. McClain DA, Hug CC Jr.
Intravenous fentanyl kinetics. Clin Pharmacol Ther 1980; 28: 106-14. 3. Holley FO, van
Steennis C. Postoperative analgesia with fentanyl: pharmacokinetics and
pharmacodynamics of constant-rate iv and transdermal delivery. Br J Anaesth 1988; 60: 608-
13. 4. Hämmig R, Kemter A, Strasser J, et al. Use of microdoses for induction of …
clinical practice guideline. CMAJ 2018; 190: E247-57. 2. McClain DA, Hug CC Jr.
Intravenous fentanyl kinetics. Clin Pharmacol Ther 1980; 28: 106-14. 3. Holley FO, van
Steennis C. Postoperative analgesia with fentanyl: pharmacokinetics and
pharmacodynamics of constant-rate iv and transdermal delivery. Br J Anaesth 1988; 60: 608-
13. 4. Hämmig R, Kemter A, Strasser J, et al. Use of microdoses for induction of …
1. Bruneau J, Ahamad K, Goyer M-È, et al. Management of opioid use disorders: a national clinical practice guideline. CMAJ 2018; 190: E247-57. 2. McClain DA, Hug CC Jr. Intravenous fentanyl kinetics. Clin Pharmacol Ther 1980; 28: 106-14. 3. Holley FO, van Steennis C. Postoperative analgesia with fentanyl: pharmacokinetics and pharmacodynamics of constant-rate iv and transdermal delivery. Br J Anaesth 1988; 60: 608-13. 4. Hämmig R, Kemter A, Strasser J, et al. Use of microdoses for induction of buprenorphine treatment with overlapping full opioid agonist use: the Bernese method. Subst Abuse Rehabil 2016; 7: 99-105.
Can Med Assoc