CT-based radiomic features predict tumor grading and have prognostic value in patients with soft tissue sarcomas treated with neoadjuvant radiation therapy
JC Peeken, M Bernhofer, MB Spraker, D Pfeiffer… - Radiotherapy and …, 2019 - Elsevier
Purpose In soft tissue sarcoma (STS) patients systemic progression and survival remain
comparably low despite low local recurrence rates. In this work, we investigated whether
quantitative imaging features (“radiomics”) of radiotherapy planning CT-scans carry a
prognostic value for pre-therapeutic risk assessment. Methods CT-scans, tumor grade, and
clinical information were collected from three independent retrospective cohorts of 83 (TUM),
87 (UW) and 51 (McGill) STS patients, respectively. After manual segmentation and …
comparably low despite low local recurrence rates. In this work, we investigated whether
quantitative imaging features (“radiomics”) of radiotherapy planning CT-scans carry a
prognostic value for pre-therapeutic risk assessment. Methods CT-scans, tumor grade, and
clinical information were collected from three independent retrospective cohorts of 83 (TUM),
87 (UW) and 51 (McGill) STS patients, respectively. After manual segmentation and …
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