Cadmium induced mitochondrial injury and apoptosis in vero cells: protective effect of diallyl tetrasufide from garlic

P Murugavel, L Pari, SL Sitasawad, S Kumar… - … International Journal of …, 2007 - Elsevier
Oxidative stress and mitochondrial injury has been implicated in cadmium-induced
apoptosis. In this study, we examined the protective effect of diallyl tetrasulfide from garlic on
cadmium induced oxidative stress and apoptosis in vero cells. Exposure of vero cells to
cadmium (10μM) for 18h showed the apoptotic events such as loss of cell viability,
alterations in nuclear morphology and decreased mitochondrial membrane potential with
significantly increased levels of reactive oxygen species (super oxide anion and hydrogen …

Cadmium induced mitochondrial injury and apoptosis in vero cells: protective effect of diallyl tetrasufide from garlic.

PM Ponnusamy Murugavel, LP Leelavinothan Pari… - 2006 - cabidigitallibrary.org
Oxidative stress and mitochondrial injury has been implicated in cadmium-induced
apoptosis. In this study, we examined the protective effect of diallyl tetrasulfide from garlic on
cadmium induced oxidative stress and apoptosis in vero cells. Exposure of vero cells to
cadmium (10 µM) for 18 h showed the apoptotic events such as loss of cell viability,
alterations in nuclear morphology and decreased mitochondrial membrane potential with
significantly increased levels of reactive oxygen species (super oxide anion and hydrogen …
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