Calpain activity in leukocytes is associated with diabetes biochemical markers
AM Salazar, P Pánico, AL Burns… - Archives of Medical …, 2019 - Elsevier
Background and Aims CAPN10 gene is associated with type 2 diabetes (T2D). Specific
members of the calpain system (CAPN1, CAPN2 and CAPN10) are implicated in glucose
metabolism. The aim of this study was to evaluate the calpain activity in leukocytes of control
subjects and patients with T2D and its association with the calpain family members involved
in glucose metabolism and with biochemical parameters that are altered in T2D. Methods
Calpain activity under extracellular glucose concentrations (70–280 mg/dL) was evaluated …
members of the calpain system (CAPN1, CAPN2 and CAPN10) are implicated in glucose
metabolism. The aim of this study was to evaluate the calpain activity in leukocytes of control
subjects and patients with T2D and its association with the calpain family members involved
in glucose metabolism and with biochemical parameters that are altered in T2D. Methods
Calpain activity under extracellular glucose concentrations (70–280 mg/dL) was evaluated …
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