human β-defensin-1 (DEFB1) was found to be significantly down-regulated in conventional
clear cell (renal) carcinoma. We have now completed an expanded expression analysis of
this gene. We performed immunohistochemical analysis for the DEFB1 protein in clinical
specimens of both renal cell carcinoma and prostate cancer. In a subset of prostate cancers,
we performed laser capture microdissection and RT-PCR to correlate mRNA levels with …