Atherosclerosis is a systemic disease in which focal lesions in arteries promote the build-up
of lipoproteins and cholesterol they are transporting. The development of atheroma
(atherogenesis) narrows blood vessels, reduces the blood supply and leads to
cardiovascular diseases. According to the World Health Organization (WHO), cardiovascular
diseases are the leading cause of death, which has been especially boosted since the
COVID-19 pandemic. There is a variety of contributors to atherosclerosis, including lifestyle …

Primary open-angle glaucoma (POAG) is the most common form of glaucoma. This condition
leads to optic nerve degeneration and eventually to blindness. Tobacco smoking, alcohol
consumption, fast-food diets, obesity, heavy weight lifting, high-intensity physical exercises,
and many other bad habits are lifestyle-related risk factors for POAG. By contrast, moderate-
intensity aerobic exercise and the Mediterranean diet can alleviate POAG. In this work, we
for the first time estimated the phylostratigraphic age indices (PAIs) of all 153 POAG-related …