Case 38-2007: A 44-Year-Old Woman with Generalized, Painful, Ulcerated Skin Lesions
V Liu, CS Cutler, AZ Young - New England Journal of Medicine, 2007 - Mass Medical Soc
V Liu, CS Cutler, AZ Young
New England Journal of Medicine, 2007•Mass Medical SocA 44-year-old woman was admitted to this hospital because of generalized, painful,
ulcerated skin lesions. Four years before admission, she had generalized hyperkeratotic
lesions that responded poorly to treatment. Biopsy specimens had been interpreted as
squamous-cell carcinoma. Three months before admission, mycophenolate mofetil was
begun; some of the lesions regressed, but 1 month later, new painful nodules and plaques
developed, with central necrosis and ulceration.
ulcerated skin lesions. Four years before admission, she had generalized hyperkeratotic
lesions that responded poorly to treatment. Biopsy specimens had been interpreted as
squamous-cell carcinoma. Three months before admission, mycophenolate mofetil was
begun; some of the lesions regressed, but 1 month later, new painful nodules and plaques
developed, with central necrosis and ulceration.
A 44-year-old woman was admitted to this hospital because of generalized, painful, ulcerated skin lesions. Four years before admission, she had generalized hyperkeratotic lesions that responded poorly to treatment. Biopsy specimens had been interpreted as squamous-cell carcinoma. Three months before admission, mycophenolate mofetil was begun; some of the lesions regressed, but 1 month later, new painful nodules and plaques developed, with central necrosis and ulceration.
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