Host adaptive immunity deficiency in severe pandemic influenza

…, J Rello, A Antón, R Almansa, L Xu, G Lopez-Campos… - Critical Care, 2010 - Springer
Abstract Introduction Pandemic A/H1N1/2009 influenza causes severe lower respiratory
complications in rare cases. The association between host immune responses and clinical
outcome in severe cases is unknown. Methods We utilized gene expression, cytokine
profiles and generation of antibody responses following hospitalization in 19 critically ill
patients with primary pandemic A/H1N1/2009 influenza pneumonia for identifying host
immune responses associated with clinical outcome. Ingenuity pathway analysis 8.5 …

Prognostic value of peak and post-exercise treadmill exercise echocardiography in patients with known or suspected coronary artery disease

…, FJ Broullon, A Garcia-Campos… - European heart …, 2010 - academic.oup.com
Aims Although peak may have higher sensitivity than post-treadmill exercise
echocardiography (EE) for the detection of coronary artery disease (CAD), its prognostic
value remains unknown. We sought to assess the relative values of peak and post-EE for
predicting outcome in patients with known/suspected CAD. Methods and results We studied
2947 patients who underwent EE. Wall motion score index (WMSI) was evaluated at rest,
peak, and post-exercise. Ischaemia was defined as the development of new or worsening …
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