Cationic polyhedral oligomeric silsesquioxane (POSS) units as carriers for drug delivery processes
C McCusker, JB Carroll, VM Rotello - Chemical Communications, 2005 - pubs.rsc.org
C McCusker, JB Carroll, VM Rotello
Chemical Communications, 2005•pubs.rsc.orgQuaternary ammonium functionalized polyhedral oligomeric silsesquioxane
(OctaAmmonium–POSS®) units, widely employed as additives in ceramic and polymeric
systems, possess many attributes which make them attractive as biocompatible drug
carriers: nanoscale size, three-dimensional functionality, efficient cellular uptake, low
toxicity, and high solubility.
(OctaAmmonium–POSS®) units, widely employed as additives in ceramic and polymeric
systems, possess many attributes which make them attractive as biocompatible drug
carriers: nanoscale size, three-dimensional functionality, efficient cellular uptake, low
toxicity, and high solubility.
Quaternary ammonium functionalized polyhedral oligomeric silsesquioxane (OctaAmmonium–POSS®) units, widely employed as additives in ceramic and polymeric systems, possess many attributes which make them attractive as biocompatible drug carriers: nanoscale size, three-dimensional functionality, efficient cellular uptake, low toxicity, and high solubility.
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