… Thus, a four-tryptophan-substitution mutant (CAM-W) from CAM was developed via the …
acid residues to enhance the antimicrobial potency and to improve the proteolytic stability of this …

… to be made to improve the antibacterial activity of CeA. In this study, nine mutant peptides of
… To determine the resistance of PEW300 to proteolytic digestion, we treated the peptide with …

… CAM-W shows more potent antimicrobial activity against … improved proteolytic stability under
a series of proteases, including trypsin, pepsin, and the Staphylococcus aureus V8 protease…

… , cecropin A and melittin, shows a better antimicrobial … Since mutations in the N-terminal
α-helices of Hpa1 Xoo and HpaG of … While stability to protease digestion is generally a desirable …

… MT-W showed increased antibacterial activity, stability, lower … A previous study synthesized
Cecropin A-Melittin mutant (… was significantly better than MT in tolerance to proteases (p < …

… cells and are readily degraded by proteases [32], various … degradation of CeA by proteases
to improve its expression. High-… -ELK16 system to induce and increase the formation of active …

… have been used to improve the proteolytic stability of AMPs, … progress made in improving
the proteolytic stability of AMPs … SHf mutant by inserting a cysteine disulfide bond, this mutant …

… in poultry feed, which are generally used to increase the growth … mutations, and in some
instances exhibit synergistic effects … and chances of degradation by host protease (in humans). …

… bacterial mutation rate induced by treatments with antibiotics … Peptide stability against
proteolysis can also be achieved by … considered an improvement able to enhance peptide stability, …

… five mutations, had strongly increased antimicrobial activity … antimicrobial activity of Cecropin
B, Cecropin P1and Melittin … ways to improve proteolytic stability of cationic antimicrobial …