Cefepime therapy for monomicrobial Enterobacter cloacae bacteremia: unfavorable outcomes in patients infected by cefepime-susceptible dose-dependent isolates

NY Lee, CC Lee, CW Li, MC Li, PL Chen… - Antimicrobial agents …, 2015 - Am Soc Microbiol
ABSTRACT A new category of cefepime susceptibility, susceptible dose dependent (SDD),
for Enterobacteriaceae, has been suggested to maximize its clinical use. However, clinical
evidence supporting such a therapeutic strategy is limited. A retrospective study of 305
adults with monomicrobial Enterobacter cloacae bacteremia at a medical center from 2008
to 2012 was conducted. The patients definitively treated with in vitro active cefepime (cases)
were compared with those treated with a carbapenem (controls) to assess therapeutic …

Cefepime therapy for monomicrobial Enterobacter cloacae bacteremia: unfavorable outcomes in patients infected by cefepime-susceptible dose-dependent isolates.

LNY Lee NanYao, LCC Lee ChingChi… - 2015 - cabidigitallibrary.org
A new category of cefepime susceptibility, susceptible dose dependent (SDD), for
Enterobacteriaceae, has been suggested to maximize its clinical use. However, clinical
evidence supporting such a therapeutic strategy is limited. A retrospective study of 305
adults with monomicrobial Enterobacter cloacae bacteremia at a medical center from 2008
to 2012 was conducted. The patients definitively treated with in vitro active cefepime (cases)
were compared with those treated with a carbapenem (controls) to assess therapeutic …
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