Cell migration, viability and tissue reaction of calcium hypochlorite based-solutions irrigants: An in vitro and in vivo study
GBF Blattes, LB Mestieri, DE Böttcher, ACM Fossati… - Archives of oral …, 2017 - Elsevier
Objective This study aimed to analyze in vitro cytotoxicity to cultured 3T3 fibroblasts and in
vivo inflammatory reaction in rats by calcium hypochlorite (Ca (OCl) 2) solutions compared
with sodium hypochlorite (NaOCl) solutions. Design Cultured 3T3 fibroblasts were exposed
to different concentrations of (Ca (OCl) 2) and NaOCl solutions, and a scratch assay was
performed. The viability rate was analyzed with trypan blue assay. Both solutions of 1% and
2.5% concentrations were injected into the subcutaneous tissue of 18 male Wistar rats aged …
vivo inflammatory reaction in rats by calcium hypochlorite (Ca (OCl) 2) solutions compared
with sodium hypochlorite (NaOCl) solutions. Design Cultured 3T3 fibroblasts were exposed
to different concentrations of (Ca (OCl) 2) and NaOCl solutions, and a scratch assay was
performed. The viability rate was analyzed with trypan blue assay. Both solutions of 1% and
2.5% concentrations were injected into the subcutaneous tissue of 18 male Wistar rats aged …
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