… cell sheet manipulation – cell sheet engineering – should prove useful as a fundamental,
generalized technique in next-generation tissue engineering and regenerative medicine. …

… of living cells via simple temperature changes. Using cultured cell sheets harvested from
temperature-responsive surfaces, we have established cell sheet engineering to create …

… cell sheets, we have exploited intelligent culture surfaces, from which cultured cells detach
as a cell sheet … In this paper, we present the new technology “cell sheet engineering” and its …

… of the cell sheet engineering-based … engineering, as well as between academia and
industry. This review describes our efforts to enable clinical applications of cell sheet engineering-…

… Using cell sheet engineering we can thus altogether avoid the need for conventional tissue
engineering approaches using isolated cell injections and scaffold-based technologies, …

… responsive culture dish” which enables reversible cell adhesion to and detachment from the
… cells as an intact monolayer cell sheet including deposited ECM. The monolayer cell sheet …

… Cell sheet tissue engineering is a concept for creating … cell sheet tissue engineering in terms
of the chemical and physical effects of material surfaces and the interfacial properties of cell …

… cell biology and cell sheet engineering, in which a temperature-responsive intelligent polymer
is grafted onto the surface of cell culture dish to create a ‘cell sheet… a contiguous cell sheet, …

… cell sheet engineering as scaffoldless tissue engineering, and applied it for myocardial tissue
engineering. … culture surfaces, cells can be harvested as intact sheets and cell-dense thick …

… cell-based constructs. We believe that the various applications of cell sheet engineering will
… have limited conventional approaches and establish a new basis for cell-based therapies. …