Exposure to the herbicide paraquat (PQ) is associated with an increased risk of idiopathic
Parkinson's disease (PD). Therapies based on PQ's presumed mechanisms of action have
not, however, yielded effective disease therapies. Cellular senescence is an anticancer
mechanism that arrests proliferation of replication-competent cells and results in a pro-
inflammatory senescence-associated secretory phenotype (SASP) capable of damaging
neighboring tissues. Here, we demonstrate that senescent cell markers are preferentially …