Characterising sex differences of autosomal DNA methylation in whole blood using the Illumina EPIC array
Background Sex differences are known to play a role in disease aetiology, progression and
outcome. Previous studies have revealed autosomal epigenetic differences between males
and females in some tissues, including differences in DNA methylation patterns. Here, we
report for the first time an analysis of autosomal sex differences in DNAme using the Illumina
EPIC array in human whole blood by performing a discovery (n= 1171) and validation (n=
2471) analysis. Results We identified and validated 396 sex-associated differentially …
outcome. Previous studies have revealed autosomal epigenetic differences between males
and females in some tissues, including differences in DNA methylation patterns. Here, we
report for the first time an analysis of autosomal sex differences in DNAme using the Illumina
EPIC array in human whole blood by performing a discovery (n= 1171) and validation (n=
2471) analysis. Results We identified and validated 396 sex-associated differentially …
以上显示的是最相近的搜索结果。 查看全部搜索结果