Characteristic molecular signature for the early detection and prediction of polycyclic aromatic hydrocarbons in rat liver

KH Jung, JK Kim, JH Noh, JW Eun, HJ Bae, MG Kim… - Toxicology letters, 2013 - Elsevier
Predictions of toxicity are central for the assessment of chemical toxicity, and the effects of
environmental toxic compounds are still a major issue for predicting potential human health
risks. Among the various environmental toxicants, polycyclic aromatic hydrocarbons (PAHs)
are an important class of environmental pollutant, and many PAHs are known or suspected
carcinogens. In the present study, to investigate whether characteristic expression profiles of
PAHs exist in rat liver and whether a characteristic molecular signature can discriminate and …
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