Characterization of Markers of Chloroquine Resistance in Plasmodium Falciparum among Pregnant Women in Oyo State: Any Hope of Chloroquine Resistance …

MM Azeez, FO Akinbo - Biomedical and Biotechnology Research …, 2022 - journals.lww.com
Background: Chloroquine (CQ) which is one of the 4-aminoquinolines was once the
mainstay of malaria treatment before it was officially withdrawn due to widespread
resistance to it by Plasmodium species. It is one of the cheapest, safest, easily produced
antimalarial compounds and has one of the longest half-lives among the antimalarial drugs
which are also safe for use in pregnancy. Reversal of CQ resistance back to sensitivity has
been documented after a period of withdrawal, and this may be a great relief in achievement …
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