Characterization of amyloid-β deposits in bovine brains

EV Costassa, M Fiorini, G Zanusso… - Journal of …, 2016 - content.iospress.com
… are identical in bovines and humans, the detection of senile plaques in cattle might be expected
[9, … The aims of the present study were to characterize Aß deposition in cattle brain and …

Characterization of amyloid-β deposits in bovine brains

E Vallino Costassa, M Fiorini… - Journal of …, 2016 - content.iospress.com
… The aims of the present study were to characterize Aβ deposition in cattle brain and correlate
Aβ fragment patterns with age, health status, and PSEN1, PSEN2, and APOE gene profiles. …

Characterization of Amyloid-β Deposits in Bovine Brains.

M Fiorini, G Zanusso, S Peletto, P Acutis… - Journal of Alzheimer's …, 2016 - europepmc.org
… The aims of the present study were to characterize Aβ deposition in cattle brain and correlate
Aβ fragment patterns with age, health status, and PSEN1, PSEN2, and APOE gene profiles. …

CHARACTERIZATION OF BETA AMYLOID DEPOSITION PROCESS IN THE BOVINE BRAIN: NEUROPATHOLOGICAL, IMMUNOBIOCHEMICAL AND GENETIC …

C Porcario - 2013 - air.unimi.it
… or as a microscopic deposit. For instance, localized AL-amyloidosis is characterized by limited
growth of monoclonal plasma cells and restriction of amyloid deposits to the adjacent sites …

Aged cattle brain displays Alzheimer's disease-like pathology and promotes brain amyloidosis in a transgenic animal model

I Moreno-Gonzalez, G Edwards III, R Morales… - Frontiers in aging …, 2022 - frontiersin.org
… , we characterized the brains from many cows at different ages for the presence of amyloid
deposits … old cows spontaneously develop amyloid deposits in their brain. Interestingly, these …

Amyloid precursor protein, lipofuscin accumulation and expression of autophagy markers in aged bovine brain

D De Biase, A Costagliola, TB Pagano, G Piegari… - BMC veterinary …, 2017 - Springer
… [21] characterized the nature of Amyloid β (Aβ) deposits in aged bovine brains pointing out
that … Furthermore, western blot analysis showed an increased level of APP in aged animal …

High sensitivity analysis of amyloid-beta peptide composition in amyloid deposits from human and PS2APP mouse brain

A Güntert, H Döbeli, B Bohrmann - Neuroscience, 2006 - Elsevier
characterized by a wide array of neuropsychiatric alterations, the most dominant being memory
loss. Pathologically, AD brains show extracellular protein deposits of amyloid-β … % bovine

Human amyloid-β enriched extracts: evaluation of in vitro and in vivo internalization and molecular characterization

CM Pedrero-Prieto, A Flores-Cuadrado… - Alzheimer's research & …, 2019 - Springer
… (AD) is characterized by the deposition of insoluble forms of amyloid-β (Aβ) in the brain
triggered by Aβ deposits [56]. This protein could be a promising focus for future treatments. …

Passage of human amyloid β-protein 1–40 across the murine blood-brain barrier

LM Maness, WA Banks, MB Podlisny, DJ Selkoe… - Life sciences, 1994 - Elsevier
… -dense cores of senile plaques of AD brains (22), deposits of AB in the cerebral blood vessels
of … of brain supernatants, obtained by ultracentrifugation, radioactivity was characterized by …

A subcutaneous cellular implant for passive immunization against amyloid-β reduces brain amyloid and tau pathologies

A Lathuiliere, V Laversenne, A Astolfo, E Kopetzki… - Brain, 2016 - academic.oup.com
… mAb-11 showed specific binding to brain amyloid deposits ( Fig. 2 A), … analysis of brain
homogenates demonstrates a significant reduction in the amount of amyloid-β 42 and amyloid-β