World Health Organization appreciated the importance of medicinal plants for public health care in developing nations. Eclipta alba (Bhringaraja) having important role in the traditional Ayurvedic and Unani systems of holistic health and herbal medicine of the east. The principal constituents of Eclipta alba are coumestan derivatives like wedololactone [1.6%], demethylwedelolactone, desmethyl-wedelolactone-7glucoside and other constituents are ecliptal, ß-amyrin, luteolin-7-O-glucoside, hentriacontanol, heptacosanol, stigmasterol. All the parts of Eclipta alba and chemical constituents are used as anticancer, antileprotic, analgesic, antioxidant, antimyotoxic, antihaemorrhagic, antihepatotoxic, antiviral, antibacterial, spasmogenic, hypotensive, ovicidal, promoter for blackening and growth of hair. This article highlights chief constituents their biological activities, uses of various parts, pharmacological activities, toxicity and clinical studies of Eclipta alba.