Chemical structure of three basic Asp-49 phospholipases A2 isolated from Crotalus molossus nigrescens venom with cytotoxic activity against cancer cells
F Lazcano-Pérez, E Rangel-López, B Robles-Bañuelos… - Toxicon, 2022 - Elsevier
Snake venoms are complex mixtures of molecules with several biological activities. Among
these molecules, the enzymes with phospholipase A 2 activity have been extensively
studied in the venoms from snakes because of their importance in the envenomation
process and symptoms. The Mexican rattlesnake Crotalus molossus nigrescens is widely
distributed in the Mexican plateau. Unlike other crotalids, its venom components have been
poorly studied. Here, we characterized the phospholipase activity of one fraction isolated …
these molecules, the enzymes with phospholipase A 2 activity have been extensively
studied in the venoms from snakes because of their importance in the envenomation
process and symptoms. The Mexican rattlesnake Crotalus molossus nigrescens is widely
distributed in the Mexican plateau. Unlike other crotalids, its venom components have been
poorly studied. Here, we characterized the phospholipase activity of one fraction isolated …
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