PURPOSE: To evaluate the outcomes for patients with Stage II breast cancer and one to
three positive lymph nodes after mastectomy who were treated with observation or adjuvant
radiotherapy to the chest wall (CW) with or without the regional lymphatics. METHODS AND
MATERIALS: We retrospectively analyzed 238 patients with Stage II breast cancer (one to
three positive lymph nodes) treated with mastectomy at the Massachusetts General Hospital
between 1990 and 2004. The estimates of locoregional recurrence (LRR), disease-free …

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