Study on the therapeutic index and synergistic effect of Chitosan-zinc oxide nanomicellar composites for drug-resistant bacterial biofilm inhibition

M Mehta, D Allen-Gipson, S Mohapatra, M Kindy… - International Journal of …, 2019 - Elsevier
… Micellar CZNPs were formed prior to biofilm treatment using a 1:3 ratio of ZnO to chitosan
nanoparticles. CZNPs were synthesized by modifying the core-shell using a self-assembly …

Vancomycin and curcumin-loaded zinc oxide functionalized chitosan carrier for the treatment of multi-drug resistant bacterial infection

P Nandhini, RD Ramya, M Murugan… - Journal of Materials …, 2023 - Springer
Zinc oxide nanoparticles (ZnO) are currently being explored in different formulations due to
… -loaded Zinc oxide nanoparticle functionalized chitosan carrier was given in Scheme S1. …

A streamlined study on chitosan-zinc oxide nanomicelle properties to mitigate a drug-resistant biofilm protection mechanism

A Limayem, SB Patil, M Mehta, F Cheng… - Frontiers in …, 2020 - frontiersin.org
… is a promising cure of … drug resistant wound infections and oral cavities) Our further future
studies will continue to validate CZNPs' broad-spectrum capability and effect on other microbes

ZnO/chitosan nanocomposites as a new approach for delivery LL37 and evaluation of the inhibitory effects against biofilm-producing Methicillin-resistant …

S Rashki, EA Dawi, MR Zilaei… - International Journal of …, 2023 - Elsevier
… failures and makes MRSA a main health problem [9] Antibiotic resistance limits treatment
chitosan nanoparticles are titanium dioxide, zinc oxide, silicon dioxide, silver, and copper oxide

A chitosan‐based hydrogel containing zinc oxide nanoparticles as a carrier for improving antibacterial activity and controlling the release of antibiotics

A Rastegari, F Hasanshakir, Z Mohammadi… - Micro & Nano …, 2023 - Wiley Online Library
resistance. In this study, the authors prepared and characterized a chitosan-based hydrogel
loaded with zinc oxide … or treating infections with high doses leads to drug resistance [2, 3]. …

Tailoring of novel azithromycin-loaded zinc oxide nanoparticles for wound healing

MS Saddik, MMA Elsayed, MA El-Mokhtar, H Sedky… - Pharmaceutics, 2022 - mdpi.com
… In addition, MIC of the free drug and nano formulation was determined. The lowest … -healing
characteristics of the formulations, different groups of wounded rats received daily treatment

Chitosan oligomer and zinc oxide nanoparticle compositions for treating drug resistant bacteria and biofilm

SS Mohapatra, A Limayem - 2020 - digitalcommons.usf.edu
… -chitosan and zinc oxide formulated as nanoparticles and … The invention also relates to the
treatment of multi-drug resistant … is a nanoparticle formulation for treating multi-drug resistant

Cationic chitosan-propolis nanoparticles alter the zeta potential of S. epidermidis, inhibit biofilm formation by modulating gene expression and exhibit synergism with …

TH Ong, E Chitra, S Ramamurthy, CCS Ling, SP Ambu… - PloS one, 2019 - journals.plos.org
antibiotic treatment dose by at least 4-fold in combination therapies thereby opening up
ways of tackling antibiotic resistance in bacteria. … Zinc oxide nanoparticles with positive zeta …

Novel composite of nano zinc oxide and nano propolis as antibiotic for antibiotic-resistant bacteria: a promising approach

SA Salama, D Essam, AI Tagyan, AA Farghali… - Scientific Reports, 2024 - nature.com
This study proposes an innovative approach to combat the escalating threat of antibiotic
resistance in bacteria by introducing a novel ZnO-propolis nanocomposite (ZnO-P NCs). The …

Biosynthesis of Zinc Oxide Nanoparticles from Acacia nilotica (L.) Extract to Overcome Carbapenem-Resistant Klebsiella Pneumoniae

E Rasha, AO Monerah, A Manal, A Rehab… - Molecules, 2021 - mdpi.com
… in the multidrug-resistant organisms’ CRE, which are generally difficult to treat, particularly
… These organisms now constitute a high risk regarding antibiotic resistance in the United …