Choosing the optimal wall shear parameter for the prediction of plaque location—A patient-specific computational study in human left coronary arteries

F Rikhtegar, JA Knight, U Olgac, SC Saur… - Atherosclerosis, 2012 - Elsevier
OBJECTIVE: While the correlation of atherosclerotic plaque locations with local wall shear
stress magnitude has been evaluated previously by other investigators in both right (RCA)
and left coronary arteries (LCA), the relative performance of average wall shear stress
(AWSS), average wall shear stress gradient (AWSSG), oscillatory shear index (OSI) and
relative residence time (RRT) as indicators of potential atherosclerotic plaque locations has
not been studied for the LCA. Here we determine the performance of said wall shear …

Choosing the optimal wall shear parameter for the prediction of plaque location—a patient-specific computational study in human right coronary arteries

J Knight, U Olgac, SC Saur, D Poulikakos… - Atherosclerosis, 2010 - Elsevier
BACKGROUND: Average wall shear–stress (AWSS), average wall shear–stress gradient
(AWSSG), oscillatory shear index (OSI) and relative residence time (RRT) are believed to
predict areas vulnerable to plaque formation in the coronary arteries. Our aim was to
analyze the correlation of these parameters in patients' vessels before the onset of
atherosclerosis to the specific plaque sites thereafter, and to compare the parameters'
sensitivity and positive predictive value. METHODS: We obtained 30 patient-specific …
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