Chronic and acute stress responses in Senegalese sole (Solea senegalensis): the involvement of cortisol, CRH and CRH-BP
YS Wunderink, S Engels, S Halm, M Yúfera… - General and …, 2011 - Elsevier
The hypothalamus-pituitary-interrenal (HPI) axis is pivotal in the endocrine stress response
of fish. Hypothalamic corticotropin-releasing hormone (CRH) initiates the endocrine stress
response and stimulates the release of adrenocorticotropic hormone (ACTH) from the
pituitary pars distalis, which in turn activates cortisol production and release by the interrenal
cells of the head kidney. CRH activity depends on the levels of a specific CRH binding
protein (CRH-BP). We have characterized the cDNAs coding for CRH and CRH-BP in …
of fish. Hypothalamic corticotropin-releasing hormone (CRH) initiates the endocrine stress
response and stimulates the release of adrenocorticotropic hormone (ACTH) from the
pituitary pars distalis, which in turn activates cortisol production and release by the interrenal
cells of the head kidney. CRH activity depends on the levels of a specific CRH binding
protein (CRH-BP). We have characterized the cDNAs coding for CRH and CRH-BP in …
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