Climbing the evidence pyramid: dosing considerations for medical cannabis in the management of chronic pain

S Jugl, AJ Goodin, JD Brown - Medical Cannabis and Cannabinoids, 2023 - karger.com
Medical Cannabis and Cannabinoids, 2023karger.com
Chronic pain is a prevalent condition, affecting more than 30% of people worldwide [1].
Medical cannabis (MC) has emerged as an increasingly available potential treatment option,
with moderate evidence supporting its effectiveness in treating chronic pain, particularly
neuropathic pain [2, 3]. However, the lack of clinical studies on MC, combined with the
various compositions, routes of administration, and individual patient factors, makes it
difficult to identify the appropriate dose of cannabis to treat chronic pain. This poses a …
Chronic pain is a prevalent condition, affecting more than 30% of people worldwide [1]. Medical cannabis (MC) has emerged as an increasingly available potential treatment option, with moderate evidence supporting its effectiveness in treating chronic pain, particularly neuropathic pain [2, 3]. However, the lack of clinical studies on MC, combined with the various compositions, routes of administration, and individual patient factors, makes it difficult to identify the appropriate dose of cannabis to treat chronic pain. This poses a significant challenge for healthcare professionals, patients, and caregivers when initiating and titrating MC treatment for chronic pain. Physicians and patients have expressed a need for more guidance regarding the dosing of MC, and the lack
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