Clinically significant bleeding in incurable cancer patients: effectiveness of hemostatic radiotherapy

N Cihoric, S Crowe, S Eychmüller, DM Aebersold… - Radiation …, 2012 - Springer
Background This study was performed to evaluate the outcome after hemostatic
radiotherapy (RT) of significant bleeding in incurable cancer patients. Methods Patients
treated by hemostatic RT between November 2006 and February 2010 were retrospectively
analyzed. Bleeding was assessed according to the World Health Organization (WHO) scale
(grade 0= no bleeding, 1= petechial bleeding, 2= clinically significant bleeding, 3= bleeding
requiring transfusion, 4= bleeding associated with fatality). The primary endpoint was …

[引用][C] Clinically Significant Bleeding in Incurable Cancer Patients: Effectiveness of Hemostatic Radiation Therapy

N Cihoric, S Crowe, S Eychmüller… - International Journal of …, 2012 - redjournal.org
Results Overall 62 patients were analyzed including 1 patient whose benign cause of
bleeding was pseudomyxoma peritonei. Median age was 66 years (range, 37-93 years).
Before RT, bleeding was graded as 2 and 3 in 24 (39%) and 38 (61%) patients, respectively.
A median dose of 20 Gy (range, 5-45 Gy) of hemostatic RT was applied to the bleeding site.
At the end of RT, there was a statistically significant difference in bleeding (p< 0.001); it was
graded as 0 (n= 39), 1 (n= 12), 2 (n= 6), 3 (n= 4) and 4 (n= 1). With a median follow-up of …
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