Clonally related follicular lymphomas and histiocytic/dendritic cell sarcomas: evidence for transdifferentiation of the follicular lymphoma clone
AL Feldman, DA Arber, S Pittaluga… - Blood, The Journal …, 2008 - ashpublications.org
Rare cases of histiocytic and dendritic cell (H/DC) neoplasms have been reported in patients
with follicular lymphoma (FL), but the biologic relationship between the 2 neoplasms is
unknown. We studied 8 patients with both FL and H/DC neoplasms using
immunohistochemistry, fluorescence in situ hybridization (FISH) for t (14; 18), and
polymerase chain reaction (PCR)/sequencing of BCL2 and IGH rearrangements. There
were 5 men and 3 women (median age, 59 years). All cases of FL were positive for t (14; …
with follicular lymphoma (FL), but the biologic relationship between the 2 neoplasms is
unknown. We studied 8 patients with both FL and H/DC neoplasms using
immunohistochemistry, fluorescence in situ hybridization (FISH) for t (14; 18), and
polymerase chain reaction (PCR)/sequencing of BCL2 and IGH rearrangements. There
were 5 men and 3 women (median age, 59 years). All cases of FL were positive for t (14; …
[引用][C] Clonally related follicular lymphomas and histiocytic/dendritic cell sarcomas: evidence for transdifferentiation of the follicular lymphoma clone. Commentary
R MAHIEUX, AL FELDMAN, DA ARBER… - Blood, 2008 - pascal-francis.inist.fr
Clonally related follicular lymphomas and histiocytic/dendritic cell sarcomas : evidence for
transdifferentiation of the follicular lymphoma clone. Commentary … Clonally related
follicular lymphomas and histiocytic/dendritic cell sarcomas : evidence for transdifferentiation
of the follicular lymphoma clone. Commentary … Non Hodgkin lymphoma …
transdifferentiation of the follicular lymphoma clone. Commentary … Clonally related
follicular lymphomas and histiocytic/dendritic cell sarcomas : evidence for transdifferentiation
of the follicular lymphoma clone. Commentary … Non Hodgkin lymphoma …
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