This study examines variations in efficiency among hospitals located in western and southern Ukraine. We estimated efficiency using a nonparemetric modeling technique known as data envelopment analysis (DEA). DEA is a very powerful tool to compare relative efficiency among several economic units of study, known as decision making units (DMUS). In our current and previous research we have focused attention on comparative efficiency among hospitals and then explained variation in efficiency based on historical and cultural differences that influence managerial behavior at the hospital level of decision making. This study using current data and an expanded geographic territory provides further support to our findings from previous studies.