This work is a contribution to existing body of knowledge by investigating the compressive strength effect of replacing cement with two natural pozzolans. This is aimed at investigating the suitability of these pozzolans as an environmentally friendly alternative to cement. Bamboo Leaf Ash (BLA) was produced by burning bamboo leaves from locally available sources. Metakaolin (MK) was also prepared by calcining natural kaolin at 700 O C for 3 hours in an electric furnace and blending into fine powder. Each pozzolan was sieved using 150µm sieve and the residues were used to partially replace OPC at 5%, 10% and 15% respectively in preparing 150mm x 150mm x 150mm OPC-pozzolan concrete cubes. For each of the percentages, nine cubes were prepared for each pozzolan while nine additional were molded for the control (0% replacement); a total of 63 cubes. A mix ratio of 1: 2: 4 and water-binder ratio of 0.6 were used. Three cubes each were crushed for compressive strength test after 7, 28 and 60 days of curing respectively for each pozzolan and the averages determined. Results indicate that MK-OPC concretes perform best at 5% replacement (60-day strength was 28.2 N/mm 2) whereas BLA-OPC concretes has the best performance at 15% replacement (60-day strength was 27.0 N/mm 2). These performances compares favorably with control (60-day strength was 26.7 N/mm 2). Besides, MK-OPC concretes reported a remarkable initial gain in strength with BLAOPC concretes catching up later. The work encouraged the use of these pozzolans in concrete production to mitigate the greenhouse effect of cement production and serve as means of revenue mobilization for the locals. In addition, the mechanism of strength gain with curing age needs be captured to effectively harness the advantages that these pozzolans has to offer.