Comparative in vitro activity of plazomicin and older aminoglyosides against Enterobacterales isolates; prevalence of aminoglycoside modifying enzymes and 16S …
D Gür, U Hasdemir, A Çakar, İ Çavuşoğlu… - … and infectious disease, 2020 - Elsevier
Comparative in vitro activity of plazomicin and 4 older aminoglycosides was evaluated with
broth microdilution in 714 blood isolates from 14 hospitals in Turkey. Isolates included
Escherichia coli (n= 320), Klebsiella spp.(n= 294), Enterobacter spp.(n= 69), Serratia
marcescens (n= 20), and Citrobacter spp.(n= 11). Isolates resistant to older aminoglycosides
(n= 240) were screened for aminoglycoside modifying enzyme genes: aac (6′)-Ib, aac (3)-
Ia, aac (3)-IIa, ant (2 ″)-Ia. Isolates with high MICs for plazomicin (n= 41) were screened for …
broth microdilution in 714 blood isolates from 14 hospitals in Turkey. Isolates included
Escherichia coli (n= 320), Klebsiella spp.(n= 294), Enterobacter spp.(n= 69), Serratia
marcescens (n= 20), and Citrobacter spp.(n= 11). Isolates resistant to older aminoglycosides
(n= 240) were screened for aminoglycoside modifying enzyme genes: aac (6′)-Ib, aac (3)-
Ia, aac (3)-IIa, ant (2 ″)-Ia. Isolates with high MICs for plazomicin (n= 41) were screened for …
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