Comparison of triage strategies for HPV-positive women: Canadian cervical cancer screening trial results

SD Isidean, MH Mayrand, AV Ramanakumar… - … Biomarkers & Prevention, 2017 - AACR
Background: High-risk human papillomavirus (HR-HPV) testing has become a preferred
cervical cancer screening strategy in some countries due to its superior sensitivity over
cytology-based methods for identifying cervical intraepithelial neoplasia of grade 2 or worse
(CIN2+). Improved sensitivity has been accompanied by reductions in specificity and
concerns regarding overscreening and overtreatment of women with transient or
nonprogressing HR-HPV infections. Triage of HR-HPV+ women to colposcopy is, thus …

[PDF][PDF] Comparison of Triage Strategies for HPV-Positive Women: Canadian Cervical Cancer Screening Trial Results

AF Rodrigues, S Ratnam, F Coutlée, EL Franco - researchgate.net
Background: High-risk human papillomavirus (HR-HPV) testing has become a preferred
cervical cancer screening strategy in some countries due to its superior sensitivity over
cytologybased methods for identifying cervical intraepithelial neoplasia of grade 2 or worse
(CIN2 þ). Improved sensitivity has been accompanied by reductions in specificity and
concerns regarding overscreening and overtreatment of women with transient or
nonprogressing HR-HPV infections. Triage of HR-HPV þ women to colposcopy is, thus …
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