Comprehensive in vitro and in vivo risk assessments of chitosan microparticles using human epithelial cells and Caenorhabditis elegans
The safety of using nano-and microparticles is a developing concern. In this study, we
conducted risk assessments of chitosan microparticles (CMs) using in vitro human epithelial
cell lines and in vivo animal model, Caenorhabditis elegans. After engineering of various
CMs, we screened four CMs based on antimicrobial activity, which is a potential usage for
disease treatment caused by multidrug resistant bacteria, and evaluated for risk
assessments. CMs, with strong antimicrobial activity, and inorganic nanoparticles (SiO 2, TiO …
conducted risk assessments of chitosan microparticles (CMs) using in vitro human epithelial
cell lines and in vivo animal model, Caenorhabditis elegans. After engineering of various
CMs, we screened four CMs based on antimicrobial activity, which is a potential usage for
disease treatment caused by multidrug resistant bacteria, and evaluated for risk
assessments. CMs, with strong antimicrobial activity, and inorganic nanoparticles (SiO 2, TiO …
Comprehensive in vitro and in vivo risk assessments of chitosan microparticles using human epithelial cells and Caenorhabditis elegans.
MZX Ma ZhengXin, A Garrido-Maestu… - 2018 - cabidigitallibrary.org
The safety of using nano-and microparticles is a developing concern. In this study, we
conducted risk assessments of chitosan microparticles (CMs) using in vitro human epithelial
cell lines and in vivo animal model, Caenorhabditis elegans. After engineering of various
CMs, we screened four CMs based on antimicrobial activity, which is a potential usage for
disease treatment caused by multidrug resistant bacteria, and evaluated for risk
assessments. CMs, with strong antimicrobial activity, and inorganic nanoparticles (SiO2 …
conducted risk assessments of chitosan microparticles (CMs) using in vitro human epithelial
cell lines and in vivo animal model, Caenorhabditis elegans. After engineering of various
CMs, we screened four CMs based on antimicrobial activity, which is a potential usage for
disease treatment caused by multidrug resistant bacteria, and evaluated for risk
assessments. CMs, with strong antimicrobial activity, and inorganic nanoparticles (SiO2 …
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