Computational analysis of non-synonymous single nucleotide polymorphism in the bovine cattle kappa-casein (CSN3) gene

JB Patel, JB Chauhan - Meta Gene, 2018 - Elsevier
Background kappa-casein is candidate gene, present on chromosome 6 of cattle, play an
important role in mammary gland and properties of milk. Methods In the present study, we
used SIFT, SNAP2, PROVEAN and PolyPhen 2 computational tools which are based on
different approaches to predict deleterious nsSNPs in coding region of cattle CSN3 gene.
Furthermore, protein stability and structure were predicted by I-Mutant 2.0, MuStab,
ModPred, ConSurf, PSIPRED, MUSTER, Ramachandran plot, TM-score, FT site and …
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