Concealed renal insufficiency and adverse drug reactions in elderly hospitalized patients

A Corsonello, C Pedone, F Corica… - Archives of internal …, 2005 - jamanetwork.com
Background Adverse drug reactions (ADRs) are common causes of in-hospital
complications for elderly people. The purpose of the present study is to verify whether
concealed renal insufficiency, that is, reduction of the estimated glomerular filtration rate
(GFR) in people with normal serum creatinine levels, is a risk factor for ADRs in elderly
hospitalized patients. Methods We used data on 11 687 hospitalized patients enrolled in the
Gruppo Italiano di Farmacovigilanza nell'Anziano study. The outcomes of the study were any …
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