Concomitant medications and risk of chemotherapy‐induced peripheral neuropathy

L Sánchez‐Barroso, M Apellaniz‐Ruiz… - The …, 2019 - academic.oup.com
Background Peripheral neuropathy is the dose‐limiting toxicity of many oncology drugs,
including paclitaxel. There is large interindividual variability in the neuropathy, and several
risk factors have been proposed; however, many have not been replicated. Here we present
a comprehensive study aimed at identifying treatment and physiopathology‐related
paclitaxel‐induced neuropathy risk factors in a large cohort of well‐characterized patients.
Patients and Methods Analyses included 503 patients with breast or ovarian cancer who …

[PDF][PDF] Concomitant Medications and Risk of Chemotherapy-Induced Peripheral Neuropathy

SB LARA, M APELLANIZ-RUIZ… - Breast, 2018 - researchgate.net
Background. Peripheral neuropathy is the dose-limiting toxicity of many oncology drugs,
including paclitaxel. There is large interindividual variability in the neuropathy, and several
risk factors have been proposed; however, many have not been replicated. Here we present
a comprehensive study aimed at identifying treatment and physiopathology-related
paclitaxel-induced neuropathy risk factors in a large cohort of well-characterized patients.
Patients and Methods. Analyses included 503 patients with breast or ovarian cancer who …
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