Consistent brain ageing synthesis

T Xia, A Chartsias, SA Tsaftaris… - … Image Computing and …, 2019 - Springer
… accelerate the ageing process. The ability to separate accelerated from healthy ageing is
useful … the joint distribution of brain images and ages, and simulate aged images by a network …

Learning to synthesise the ageing brain without longitudinal data

T Xia, A Chartsias, C Wang, SA Tsaftaris… - Medical Image …, 2021 - Elsevier
synthesized aged images across decades. For brain ageing synthesis, a good synthetic brain
… We use Cam-CAN to demonstrate consistent brain age synthesis across the whole lifespan…

Factors associated with brain ageing-a systematic review

J Wrigglesworth, P Ward, IH Harding, D Nilaweera… - BMC neurology, 2021 - Springer
brain changes, or commonly referred to as brain ageing. The aim of this systematic review is
to identify and synthesize the … factors and diseases in adult populations, with brain ageing. …

Normal brain ageing: models and mechanisms

EC Toescu - … Transactions of the Royal Society B …, 2005 - royalsocietypublishing.org
… neurons there is a significant age-dependent decrease in the amount of mitochondrial dye
accumulated in the aged neurons, consistent with the concept of age-induced mitochondrial …

Ageing and the regulation of protein synthesis: a balancing act?

N Tavernarakis - Trends in cell biology, 2008 - cell.com
ageing, such … synthesis is a novel determinant of ageing in diverse organisms such as
yeast, worms, flies and mice and can thus be considered as a universal component of the ageing

Normal ageing of the brain: Histological and biological aspects

T Teissier, E Boulanger, V Deramecourt - Revue neurologique, 2020 - Elsevier
… Many studies have confirmed the consistency of their localization: the entorhinal cortex and
… been implicated in brain ageing. This pathway is involved in protein synthesis, proliferation …

The brain, sirtuins, and ageing

A Satoh, S Imai, L Guarente - Nature Reviews Neuroscience, 2017 - nature.com
… chronic microglial activation exacerbates brain ageing by inducing … Consistent with these
GWAS studies, brain-specific Sirt1-knockout … synthesis in these neurons 74 . Conditional whole-…

[HTML][HTML] Nutrition for the ageing brain: towards evidence for an optimal diet

D Vauzour, M Camprubi-Robles… - Ageing research …, 2017 - Elsevier
… to brain ageing, pathological conditions affecting brain function, and brain biomarkers are
… Activated microglia has the capacity to synthesize a wide range of pro-inflammatory and anti…

Ageing in the brain: mechanisms and rejuvenating strategies

F Gaspar-Silva, D Trigo, J Magalhaes - Cellular and Molecular Life …, 2023 - Springer
… on how systemic ageing translates into brain ageing. Finally, we … sites changing, relatively
consistently between individuals and … compromises protein and neurotransmitter synthesis. …

Evaluation of brain ageing: a quantitative longitudinal MRI study over 7 years

RM Gracien, L Nürnberger, P Hok, SM Hof, SC Reitz… - European …, 2017 - Springer
… healthy brain ageing might help to clarify when and under which conditions normal brain
ageing … For ROI-based analyses, cortical volume was defined on the basis of the synthetic MP-…